The orthopedic giant launched its fourth-generation Mako system — Mako 4 — a single robotics platform delivering additional applications and innovation. Stryker designed Mako 4 to offer a premium experience across its Total Hip, Total Knee, Partial Knee and Spine offerings. Mako 4 also integrates Stryker’s fourth-generation Q Guidance system.
Stryker unveiled this launch, plus more advancements, at the American Academy of Orthopaedic Surgeons’ (AAOS) 2025 meeting in San Diego.
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The company also expanded on the established Mako Total Hip offering to include a first-to-market robotic hip revision capability. In revision total hip arthroplasty (THA), it streamlines workflow and enables confidence in challenging procedures with new features. Those include augment and screw planning, intraoperative screw trajectory guidance and compatibility with Stryker’s revision hip implant portfolio.
Additionally, Mako Spine and Mako Shoulder join the company’s SmartRobotics suite of applications. Stryker completed its first Mako Spine cases in October 2024 and continues a limited U.S. launch. It expects a full rollout in the second half of this year. The company also completed Mako Shoulder’s first cases at the end of 2024. It is expected to remain in a limited release through 2025.
Both the spine and shoulder applications received FDA nods last year.
“Today’s advancements in Mako SmartRobotics build on a foundation of clinical impact, innovation and market leadership,” said Keith Evans, VP and GM of Stryker’s Mako and Enabling Technologies business. “We are thrilled to showcase and demonstrate the future of Mako, not only what it can do but who it serves — more surgeons, more patients, across more specialties and more procedures.”
