Regenerative medicine company CollPlant today released information on its planned initial public offering, looking to bring in $25 million. CollPlant produces wound care and regenerative devices based on plant-derived collagen. Their products include the Vergenix FG flowable gel intended to treat chronic and acute wounds. The wound-filling gel utilizes Israel-based CollPlant’s proprietary tobacco plant-based technology, […]
Regenerative Medicine
Researchers boost stem cell programming with gene mutation
Researchers discovered a way to increase the efficiency of stem cell programming using research on a rare genetic disease, according to a study published in the Proceedings of the National Academy of Sciences. Induced pluripotent stem cells are created from skin cells and can be transformed into any type of cell in the body. Using existing […]
Targazyme wins FDA clearance for Phase II bone marrow stem cell study
Targazyme said today that it will begin enrolling patients in a Phase II clinical study to evaluate TZ101-fucosylated bone marrow stem cells in cancer patients, after the FDA granted the San Diego-based company investigational new drug clearance. The treatment is designed to use blood-forming stem cells from bone marrow to restore the body’s ability to make blood […]
Cytori touts regenerative cell therapy data
Cytori Therapeutics (NSDQ:CYTX) touted the publication of preclinical safety and efficacy data for its cell therapy treatment for combined radiation and thermal injury. The San Diego-based company said the current healthcare system is ill-prepared to care for large numbers of patients that require simultaneous treatment and that patients with severe burns commonly suffer with prolonged […]
Cartiva’s water-based implant for big toe damage
(Reuters) — When the painkillers stop working, arthritic joint damage in the big toe can make even the weight of a bedsheet agonizing. Standard surgery eliminates that pain by removing the cartilage and fusing the bones, but at the expense of mobility. Cartiva Inc‘s implant – made of the same substance used in contact lenses, called […]
Orthocell wins ethics nod for CelGro trial in peripheral nerve regeneration
Orthocell (ASX:OCC) said today that it won ethics approval for a human study evaluating its CelGro collagen soft tissue repair device for peripheral nerve regeneration. The study is slated to enroll 20 patients at St. John of God Hospital at the end of the calendar year. Researchers will evaluate the safety, tolerability, and effectiveness of CelGro […]
Histogenics raises $30m for NeoCart regenerative knee treatment
Histogenics (NSDQ:HSGX) said last month that it raised $30 million in a private placement it plans to use for a pivotal trial of its NeoCart regenerative knee treatment. The Waltham, Mass.-based company said the round, of equity, convertible stock and warrants, was led by new institutional investors and some of its existing backers. The cash […]
Bioprinted 3D renal architecture recapitulates kidney function
Researchers from the Wyss Institute for Biologically Inspired Engineering at Harvard University have bioprinted a functional 3D renal architecture with living human epithelial cells. Previously, the team bioprinted tissue constructs made of living cells alongside a vascular network in an extracellular matrix. These constructs are functional in vitro for more than a month. Get the full […]
Gamida Cell wins FDA breakthrough therapy designation for NiCord cell graft
Gamida Cell said today that it won breakthrough therapy designation from the FDA for its lead product candidate, NiCord. The Jerusalem-based company’s expanded cell graft is designed to be an alternative to bone marrow transplantation for patients with high-risk hematological cancers. Gamida Cell said it plans to launch an international Phase III registration study of the […]
Harbor MedTech raises $5m for regenerative soft tissue repair tech
Harbor MedTech said yesterday that it raised nearly $5 million for the regenerative treatments for soft tissue repair it developed. The Irvine, Calif.-based company said 3 unnamed investors participated in the equity round, which aims to raise a total of nearly $8.5 million, according to a regulatory filing. Harbor developed a technique it calls “Bridge” to […]
Organovo unveils bioprinted liver transplant patches
Organovo (PINK:ONVO) today announced it is developing 3D bioprinted human liver tissue designed for direct transplantation to patients. The move to human development comes based on “strong results” from preclinical animal model studies, the San Diego, Calif.-based company said. The company expects to pursue a formal preclinical development program. “We’re excited to introduce an implantable bioprinted liver […]