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Home » The 10 largest orthopedic device companies in the world

The 10 largest orthopedic device companies in the world

May 6, 2025 By Chris Newmarker

This is a marketing image showing Johnson & Johnson MedTech’’s Velys robotic orthopedic surgery system in action.
Johnson & Johnson MedTech’’s Velys robotic orthopedic surgery system in action [Image courtesy of J&J MedTech.]
A roundup of the largest orthopedic device companies in the world has been a popular feature at MassDevice in recent years, serving as a runup to our sibling site MDO’s annual Medtech Big 100 report.

This year, we decided to take it a step further, creating a free, downloadable report with a company-by-company breakdown of the financials, tech platforms, M&A plays, and competitive strategies shaping the next era of orthopedics.

Our roundup of the world’s largest orthopedic device companies drew on information from publicly available SEC filings, news releases, and previous MassDevice reporting —  as well as direct outreach to the companies. This year, we also included privately held Arthrex by drawing on a revenue estimate from Forbes. (Arthrex declined to disclose its annual revenue.) We only included orthopedic device business revenue for conglomerates such as Johnson & Johnson, Stryker, Medtronic, and Smith+Nephew.

Johnson & Johnson MedTech, Stryker and Zimmer Biomet continue to lead the annual list of the world’s largest orthopedic device companies, but much more is going on. Here’s a peek at how the top 10 list turned out:

This is a list of the world's largest orthopedic device companies with Johnson & Johnson MedTech, Stryker, Zimmer Biomet, and Medtronic at the top.

Download our free report on the world’s largest orthopedic device companies — and get a company-by-company breakdown of the financials, tech platforms, M&A plays, and competitive strategies shaping the next era of orthopedics>>

And here are last year’s rankings>>

Filed Under: Business/Financial News, Featured, In-Depth Coverage, Orthopedics, Special Content, Spine Tagged With: Alphatec, arthrex, Arthrex Inc., DePuy Synthes, Enovis, Globus Medical, Johnson & Johnson MedTech, Medtronic, Orthofix, Smith+Nephew, Stryker, Zimmer Biomet

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About Chris Newmarker

Chris Newmarker is the executive editor of WTWH Media life science's news websites and publications including MassDevice, Medical Design & Outsourcing and more. A professional journalist of 18 years, he is a veteran of UBM (now Informa) and The Associated Press whose career has taken him from Ohio to Virginia, New Jersey and, most recently, Minnesota. He’s covered a wide variety of subjects, but his focus over the past decade has been business and technology. He holds bachelor’s degrees in journalism and political science from Ohio State University. Connect with him on LinkedIn or email at [email protected].

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