No difference in PCI on lipid-rich plaque lesions
Two-year results from a large-scale study found that PCI on lipid-rich plaque detected by near-infrared spectroscopy was not associated with subsequent major adverse cardiac events compared to PCI of non-LRPs.
The Color study enrolled nearly 1,900 patients to undergo NIRS during PCI procedures. The primary endpoint was a composite major adverse cardiac event of cardiac death, myocardial infarction, stent thrombosis, revascularization and hospitalization. The overall rate of MACE at 2 years was 14.1% for all patients, 6.0% related to the culprit lesion, 8.3% related to the non-culprit lesion related, and 2.4% indeterminate.
“In this large-scale registry, non-culprit lesion related events were a little more common than culprit lesion post-PCI related events during 2-year follow-up,” Dr. Giora Weisz, of Jerusalem’s Shaare Zedek Medical Center, said in prepared remarks. “The results also indicate that PCI of NIRS-defined lipid rich plaques was safe, and was not associated with increased peri-procedural or long-term adverse outcomes compared to PCI of non-LRPs. Additional studies are needed to determine the clinical significance of NIRS-defined non-culprit LPRs.”