Novel selective progesterone receptor modulators (SPRMs) like Allergan/Gedeon Richter’s ulipristal, Bayer’s vilaprisan and Repros’s Proellex – and gonadotropin-releasing hormone (Gn-RH) antagonists like AbbVie’s elagolix, Myovant’s relugolix and ObsEva’s OBE-2109 – are projected to be effective medical alternatives to surgical procedures. Hysterectomies and myomectomies are the current long-term management of uterine fibroids.
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