Researchers have developed a microchip imaging platform to image-analyze thousands of roundworms simultaneously, according to the Cockrell School of Engineering at the University of Texas at Austin. This is the 1st large-scale, in vivo drug discovery platform using a whole animal model, the school reported.
The study, published in Nature Communications, detailed a flexible, cellphone-sized chip with 96 wells used to immobilize drug-treated roundworms, commonly referred to as C. elegans. The chip can be used by researchers to analyze the efficacy of drugs on 3,600 live worms, at the cost of an in vitro, cell-based platform.
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