The study, published in Gastroenterology, found that the use of GI Genius in conjunction with colonoscopy significantly decreases the miss rate (2x) of colorectal polyps and adenomas compared to standard colonoscopy. GI Genius uses AI to help detect colorectal polyps during colonoscopy to potentially prevent colorectal cancer.
Adenoma miss rate (AMR) in colonoscopies performed as part of the study was significantly lower when GI Genius was used (15.5%) when compared to non-AI-assisted colonoscopy (32.4%). According to a news release, the findings demonstrate that the use of GI Genius during colonoscopy significantly decreases the miss rate of both adenomas and polyps, confirming the benefit the technology adds to colonoscopy procedures.
The study — the first U.S. trial using the GI Genius intelligent endoscopy model — also assessed false-negative rates when a GI Genius-assisted colonoscopy detected adenoma(s) after an initial standard colonoscopy did not. Those rates (6.8%) were lower than that of non-AI-assisted colonoscopies (29.6%).
Medtronic said the findings confirm topline results from the Detect study revealed in November 2021, with that data showing both AMR and polyp miss rate significantly improve when GI Genius is used during colonoscopy. Cosmo Pharmaceuticals, the developer and manufacturer of Medtronic’s GI Genius system, funded the study.
“We know that colonoscopy is the gold standard for colon cancer screening and this study unequivocally demonstrates that AI-technology can help physicians better detect polyps during the procedure,” Medtronic CMO of the Gastrointestinal business Dr. Austin Chiang said in the release. “As a gastroenterologist, I worry about missed polyps because around half of all cases of post-colonoscopy colorectal cancer may be attributed to not catching them during the index colonoscopy. The impact of missed polyps could ultimately be the difference between life and death when we consider that 90% of patients with colon cancer can beat it when it’s caught early.”