The MassDevice Weekly Checkup: February 1, 2011

Our Weekly Checkup takes the temperature of the medical device industry’s three largest U.S. clusters: Massachusetts, California and Minnesota.

The MassDevice Indices are weighted according to market capitalization, based on the number of shares outstanding for each company and each Friday’s closing share price.

The Massachusetts index for the week ended Jan. 28 closed at 6.17, down 1.1 percent compared with the prior week. Since Jan. 1, 2009, when we began tracking these companies, the index has risen 39.2 percent.

The Minnesota index for the week ended Jan. 28 closed at 3.72, down 1.6 percent compared with the prior week. Since Jan. 1, 2009, when we began tracking these companies, the index has risen 26.0 percent.

The California index for the week ended Jan. 28 closed at 9.38, up 0.1 percent compared with the prior week. Since Jan. 1, 2009, when we began tracking these companies, the index has risen 121.1 percent.

We also create a composite index of the three regional indices and compare it with four other indices (the S&P 500, the Dow Jones Industrial Average, the Dow’s IHI medical devices index and the NASDAQ exchange):

The Weekly Checkup also compares Monday morning’s opening share prices with their value when the markets close Friday afternoon to calculate the biggest gainers and losers.

The 10 biggest gainers:

1. Accuray Inc.: 18.35% (open $7.52; close $8.90)
2. Acusphere Inc.: 8.33% (open $0.06; close $0.07)
3. Cardiogenesis Corp. : 7.90% (open $0.26; close $0.28)
4. Ophthalmic Imaging Systems : 5.34% (open $0.73; close $0.77)
5. Patient Safety Technologies Inc. : 4.44% (open $0.90; close $0.94)
6. Biomerica Inc. : 2.94% (open $0.34; close $0.35)
7. Clinical Data Inc.: 1.94% (open $26.84; close $27.36)
8. American Shared Hospital Services : 1.91% (open $3.14; close $3.20)
9. Thoratec Corp. : 1.63% (open $22.76; close $23.13)
10. Zoll Medical Corp.: 1.00% (open $41.00; close $41.41)

Sources: Google Finance and Yahoo! Finance.

And the 10 biggest losers:

1. Biopure Corp.: -36.00% (open $0.01; close $0.01)
2. Cardica Inc. : -15.52% (open $4.96; close $4.19)
3. HepaLife Technologies: -10.53% (open $0.19; close $0.17)
4. Alphatec Holdings Inc. : -6.92% (open $2.60; close $2.42)
5. Cerus Corp. : -6.38% (open $3.45; close $3.23)
6. Brooks Automation Inc.: -6.10% (open $12.30; close $11.55)
7. NMT Medical Inc.: -6.02% (open $0.50; close $0.47)
8. HeartWare International Inc.: -5.81% (open $96.71; close $91.09)
9. Staar Surgical Company : -4.97% (open $5.63; close $5.35)
10. NuVasive Inc. : -4.73% (open $28.78; close $27.42)

Sources: Google Finance and Yahoo! Finance.