Tightly-packed endothelial cells line blood vessels and maintain a highly structured barrier. But researchers from Rice University, Emory University and the Georgia Institute of Technology have found a way to selectively create “leaky” blood vessels for targeted drug delivery.
The team’s study, which was published in Nature Communications, reported that magnets can help lead iron-oxide nanoparticles into endothelial cells, as well as create gaps and then close them.
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