Researchers at Boston Children’s Hospital successfully reversed Type I diabetes in a mouse model using blood stem cells, according to a study published this week in Science Translational Medicine. The researchers used cells that were pre-treated to make more of a protein, PD-L1, which is deficient in mice and people with Type I diabetes. “There’s really a reshaping […]
Stem Cells
BrainStorm enrolls first ALS patient in late-stage NurOwn trial
Brainstorm Cell Therapeutics (NSDQ:BCLI) said today that the first patients have been enrolled in its Phase III trial evaluating NurOwn as a treatment for amyotrophic lateral sclerosis, or ALS, at Massachusetts General Hospital and UC Irvine Medical Center. The trial, which is slated to enroll 200 patients, is designed to include the pre-specified patient subgroups who […]
FDA intervenes after stem cell center offers unproven treatment to cancer patients
The FDA is cracking down on stem cell clinics that administer unproven and potentially dangerous treatments to patients, citing a California-based clinic that the regulatory watchdog said was treating cancer patients with the smallpox vaccine. The only reliable treatment is this stem cell treatment therapy, it´s the only one that has been proven yet to […]
Gamida Cell launches severe aplastic anemia trial
Gamida Cell said today that the first patient has been transplanted in a study of its CordIn product for patients with severe aplastic anemia or hypoplastic myelodysplastic syndrome. The product is designed for patients with rare genetic diseases who have no fully-matched donors for a bone marrow transplantation. Gamida Cell said it is also evaluating its […]
Anika Therapeutics touts Hyalofast scaffold, stem cell combo
Anika Therapeutics (NSDQ:ANIK) touted data today from a study evaluating the use of its Hyalofast biodegradable, hyaluronic acid-based scaffold in combination with autologous adult mesenchymal stem cell therapy for cartilage lesions in the knee. The study, which was published in Knee Surgery Sports Traumatology Arthroscopy, showed that the treatment was equally effective among patients, regardless of age. […]
Researchers develop stem cell therapy to fight inflammatory lung conditions
Researchers from the UNC School of Medicine and North Carolina State University showed that they could harvest and multiply lung stem cells in volumes sufficient for human therapy. In a second study, the team used their cell therapy to treat a model of idiopathic pulmonary fibrosis. The scientists reported that they are in talks with […]
ViaCyte launches cell replacement trial for Type I diabetes
Regenerative medicine company ViaCyte said today that the first patients have been implanted in a trial of its islet cell replacement therapy, PEC-Direct. San Diego-based ViaCyte is developing the cell therapy as a functional cure for patients with Type I diabetes who are at risk of suffering acute life-threatening complications. Get the full story at our sister […]
Brainstorm adds UCal Irvine Medical Center to late-stage NurOwn trial
Brainstorm Cell Therapeutics (NSDQ:BCLI) said today that it inked an agreement with the University of California Irvine Medical Center to enroll patients in the Phase III trial of its NurOwn mesenchymal stem cell-based platform for amyotrophic lateral sclerosis. This marks the third medical center to work with Brainstorm to enroll patients in the late-stage pivotal trial. […]
Brainstorm lands $2.1m Israeli grant for NurOwn stem cell therapy
Brainstorm Cell Therapeutics (NSDQ:BCLI) said today that it landed a $2.1 million grant from the Israel Innovation Authority. The funds are slated to support the development of Brainstorm’s NurOwn mesenchymal stem cell-based platform for the treatment of neurodegenerative diseases, including ALS. This is the 10th year that Brainstorm has won grant support from the Israeli office […]
Engineered tissue could eliminate radiation for bone marrow transplants
University of California San Diego engineers have created artificial bone tissue that could eliminate the need for radiation before bone marrow transplants. Shyni Varghese, a bioengineering professor at UC San Diego Jacobs School of Engineering, led a team to develop a bone-like implant to eliminate the pre-treatment radiation that kills stem cells in a patient’s bone […]
Magenta raises $50m, inks partnership with Novartis for stem cell transplant drugs
Magenta Therapeutics said today that it closed a $50 million Series B round and licensed a clinical-stage program from Novartis (NYSE:NVS) to advance its stem cell transplantation platform. The company also inked a partnership deal with Be The Match BioTherapies. Google’s venture arm, GV, led the financing round and was joined by existing investors, including […]