Researchers at Imperial College London have developed a technique to replicate biological structures using cryogenics and 3D printing. The research is a first from the university to create structures that are soft enough to replicate the mechanical properties of organs like the brain and lungs. The 3D printing technique could create replica organs and assist […]
Regenerative Medicine
Secant Group officials think they’ve cracked vascular regeneration: Here’s how
Secant Group today announced what it described as game-changing technology to advance vascular regeneration, solving problems that surgeons presently have when it comes to vascular harvesting and the non-resorbable synthetic graft compliance mismatching. The technology, which Secant (Telford, Pa.) developed in partnership with its sister company SanaVita Medical, involves a synthetic, small bore, vessel with a […]
Study: Implantable robot helps spur tissue regeneration
An implantable, programmable robot induced cell growth and lengthened part of the esophagus in an animal model by more than 75%, according to researchers from Boston Children’s Hospital. The team reported in Science Robotics today that the robot triggered tissue growth without interfering with organ function. The system could help regrow parts of the esophagus that […]
BioCardia files 2nd FDA IDE bid for CardiAMP chronic myocardial ischemia, refractory angina study
BioCardia (NSDQ:BCDA) said today it filed for a second FDA investigational device exemption to launch a trial of its CardiAMP cell therapy of chronic myocardial ischemia and refractory angina as it seeks a second indication. The San Carlos, Calif.-based company’s CardiAMP therapy uses autologous cells to treat chronic myocardial ischemia, and is designed to stimulate the […]
These lab-grown blood vessel replacements could benefit dialysis patients
University of Minnesota researchers have developed a blood vessel replacement made of biological materials in a lab. The lab-grown vessels have no living cells at implantation and could be used as a graft for kidney dialysis patients. The lab-engineered blood vessel replacement is the first nonsynthetic, decellularized graft that is repopulated with cells using the […]
Frequency touts first-in-human safety study for hearing loss therapy
Frequency Therapeutics has finished a first-in-human study of its progenitor cell activation therapy, FX-322, in nine adults with severe to profound sensorineural hearing loss. The company’s candidate is a combination of small molecules that are designed to activate progenitor cells and trigger the formation of new hair cells in the inner ear. Get the full story […]
Histogenics inks deal to develop Neocart for the Japanese market
Histogenics (NSDQ:HSGX) has inked a deal with Medinet to develop and commercialize its Neocart implant for the Japanese market. The Waltham, Mass.-based company’s Neocart implant is designed to repair knee cartilage damage. The product is made using a patient’s own cells, harvested from the surface of the patient’s femur. Get the full story at our sister site, Drug […]
ParaGen raises $4m for regenerative medicine scaffold
ParaGen Technologies said it raised more than $4 million for the regenerative scaffold its portfolio companies use for a variety of treatments. Columbus, Ohio-based ParaGen said its four companies – RenovoDerm, Atreon Orthopedics, Vascular Genesis and Tarian Medical – tailor the scaffold material to product lines in the wound care, orthopedic, peripheral vascular and hernia markets, respectively. Ikove […]
Smith & Nephew closes $210m Rotation Medical buy
Smith & Nephew (NYSE:SNN) said today that it closed the $210 million acquisition of Rotation Medical and its regenerative shoulder repair treatment. The deal called for the British orthopedics and wound care giant to pay $125 million in up-front cash, with another $85 million on the line over the next five years in financial milestones. Plymouth, Minn.-based Rotation’s […]
Semma Therapeutics closes $114m round to advance cell therapy for Type I diabetes
Semma Therapeutics has closed an oversubscribed $114 million Series B round to help fund the development of its encapsulated stem cell-derived islet therapy for Type I diabetes. The Cambridge, Mass.-based company reported that it plans to use the newly-acquired funds to bring its cell therapy through clinical proof-of-concept studies, as well as explore other regenerative medicine […]
Fibralign closes syndicate funding round from AngelMD
Fibralign has recently closed a syndicate funding round coordinated by investment and networking platform AngelMD to support its Nanoweave 3D scaffolding tech and medical devices using the technology. The Union City, Calif.-based company’s first product is the BioBridge collagen matrix, which is an implantable, biocompatible and biodegradable surgical mesh with 510(k) clearance for use in […]