Abbott Vascular (NYSE:ABT) is laying off about 100 workers at a California plant it acquired when it bought a portion of Guidant Corp. in 2006.

The cuts are part of a restructuring plan for Abbott’s vascular, nutrition and diagnostics units (in 2011, Abbott said it would cut 2% of its global pharmaceutical workforce, eliminating about 1,900 jobs).

"We’re making adjustments to our workforce to increase efficiencies and remain competitive in a challenging global environment," spokesman Steve Kelly said in a statement, according to the Riverside Press-Enterprise.

The roster at the Temecula facility has shrunk from a peak of roughly 4,000 workers to about 1,700 since 2012, the newspaper reported. In January 2012 Abbott pared 300 workers from the operation, which makes stents, dilation catheters and other vascular devices. Those layoffs followed cuts in 2010, when Abbott eliminated 120 positions in Temecula and Murieta, Calif.

In September Abbott Vascular said it would shutter a plant in Texas and transfer production and 50 jobs to the Temecula plant. The facility in Webster, Texas, was acquired when Abbott bought IDEV Technologies last year.