Researchers from the University of Liverpool have developed a method of delivering pediatric HIV drugs using solid drug nanoparticles, according to a study published today in Nature Communications.
There are no clinically available oral nanotherapies for HIV patients and pediatric HIV medicines are not widely available, according to the researchers.
The team examined a current pediatric HIV medicine that uses ethanol to solubilize lopinavir, an antiretroviral. The drug is not easily soluble, so creating an oral formulation that can efficiently deliver the drug for treatment is tricky.
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